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母亲孕期吃花生宝宝对花生过敏机率较低

时间:2013年12月28日 信息来源:互联网 点击:

 

         据世界着名的美国权威医学期刊《美国医学会小儿科学期刊》研究论文指出,母亲孕期吃花生,小孩对花生过敏的机率会比较低。这是因为子宫内的早期接触,产生对食物的天然耐受能力。但食用前提是,母体不会对花生过敏。这项研究的对象是8200名美国儿童,其中140人对花生过敏。研究人员检视孩童母亲在孕期与分娩不久后的饮食后发现,每周摄取5份以上花生或腰果、杏仁与胡桃等其它坚果的母亲,孩子过敏的机率会低于母亲不碰坚果的小孩。研究人员认为,子宫内的早期接触,能获得对特定食物的天然耐受能力。波士顿儿童医院过敏与免疫科医师麦可杨说:“研究表现,母体在对花生不会过敏情况下摄取花生,小孩对花生过敏的风险较低。”他说:“假如母体对花生不会过敏,没有理由必须在孕期避免食用花生。”医师曩昔都建议妇女在孕期与哺乳期间避免食用花生,然而美国小儿科学会(American Academy of Pediatrics)认为,并没有充分证据足以持续呼吁怀孕妇女避免食用花生,因此这项建议已在2008年变更。
原文择要参考:

Importance  The etiology of the increasing childhood prevalence of peanut or tree nut (P/TN) allergy is unknown.

Objective  To examine the association between peripregnancy consumption of P/TN by mothers and the risk of P/TN allergy in their offspring.

Design, Setting, and Participants  Prospective cohort study. The 10?907 participants in the Growing Up Today Study 2, born between January 1, 1990, and December 31, 1994, are the offspring of women who previously reported their diet during, or shortly before or after, their pregnancy with this child as part of the ongoing Nurses’ Health Study II. In 2006, the offspring reported physician-diagnosed food allergy. Mothers were asked to confirm the diagnosis and to provide available medical records and allergy test results. Two board-certified pediatricians, including a board-certified allergist/immunologist, independently reviewed each potential case and assigned a confirmation code (eg, likely food allergy) to each case. Unadjusted and multivariable logistic regression analyses were used to evaluate associations between peripregnancy consumption of P/TN by mothers and incident P/TN allergy in their offspring.

Exposure  Peripregnancy consumption of P/TN.

Main Outcomes and Measures  Physician-diagnosed P/TN allergy in offspring.

Results  Among 8205 children, we identified 308 cases of food allergy (any food), including 140 cases of P/TN allergy. The incidence of P/TN allergy in the offspring was significantly lower among children of the 8059 nonallergic mothers who consumed more P/TN in their peripregnancy diet (≥5 times vs <1 time per month: odds ratio?=?0.31; 95% CI, 0.13-0.75; Ptrend?=?.004). By contrast, a nonsignificant positive association was observed between maternal peripregnancy P/TN consumption and risk of P/TN allergy in the offspring of 146 P/TN-allergic mothers (Ptrend?=?.12). The interaction between maternal peripregnancy P/TN consumption and maternal P/TN allergy status was statistically significant

 


 


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